FDA Approves Syndros, Marijuana In Liquid Form — But Is It More Effective Than Pills?
First marijuana pills, now a drink: The Food and Drug Administration (FDA) have approved the liquid version of dronabinol, which is essentially a man-made version of the substance's main ingredient tetrahydrocannabinol (THC). And now that THC is available in pill and liquid form, some are hoping that we're finally on our way toward universal medical marijuana use.
Per the FDA's approval earlier this month, Syndros is now available by prescription to treat anorexia associated with weight loss in AIDS patients and to relieve nausea and vomiting in chemotherapy patients who don't respond as well to conventional treatments. However, it likely won’t give users the same high as the plant form. Still, it could help people suffering from a variety of chronic ailments, like cancer, to experience some (legal) relief.
But is it too soon to celebrate? Popular Science reported that despite its name, liquid marijuana lacks many of the important components of natural marijuana, and therefore has a much weaker effect. One of the biggest drawbacks to Syndros is its lack of “the entourage effect.” THC is just one component of marijuana, but it's the combination of all marijuana’s components that give the drug its sought-after effect. Without other cannabinoids to react with, Syndros’ effects are muted.
While that may be, the drug’s FDA approval is not without its benefits. For example, there is now yet another legal option to combat pain, nausea, epileptic seizures, Alzheimer's, and other health conditions and symptoms that marijuana has previously been proven to help treat. Syndros was approved for the same reasons Marinol, a dronabinol pill first approved in 1985, was; the former decision was based on new data that shows Syndros and Marinol are processed similarly in the body. Not to mention Marinol has proven safe and effective in anorexia and cancer patients, according to the FDA.
But what's interesting about the liquid form is that may be easier for the body to absorb than original pill forms of the drug, something that could be especially useful for certain patients. There have already been more than 9,500 dronabinol prescriptions of the pill form in the U.S., and many of these may be converted to the liquid Syndros version of the drug, Motherboard reported. Since a simple drug test cannot tell the difference between synthetic and natural THC, having a prescription for the medication could also help some individuals avoid legal trouble.
Marinol is in Schedule III under the Controlled Substances Act; however, a scheduling determination has not yet been made by the Drug Enforcement Administration for Syndros oral solution.
Correction: This article has been updated to reflect that although Marinol is in Schedule III under the Controlled Substances Act, a scheduling determination as not yet been made by the DEA for the Syndros oral solution.